SHH SIGNALING PATHWAY DRIVES PEDIATRIC BONE SARCOMA PROGRESSION

SHH Signaling Pathway Drives Pediatric Bone Sarcoma Progression

Primary bone tumors can be divided into two classes, benign and malignant.Among the latter group, osteosarcoma and Ewing sarcoma are the most prevalent malignant primary bone tumors in children and adolescents.Despite intensive efforts to improve treatments, almost 40% of patients succumb to the disease.Specifically, the clinical outcome for metast

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Theoretical-methodological conception for the development of the creative performance mode in university students

Cuban professional training allows university students to assimilate systematized content for the construction of their professional performance mode, as part of this they must express categories such as originality, flexibility, autonomy and motivation, belonging to a creative mode of performance.Teachers direct development in this way from the pl

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What does science tell us about teaching reading?

The article explores the importance of early reading proficiency and its long-term impact on academic and life outcomes, particularly in Romania.Analyzing PISA data, the article highlights significant literacy gaps between advantaged and disadvantaged students, as well as urban and rural learners.These disparities perpetuate intergenerational pover

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Nutritional and Functional Properties of Defatted Flour, Protein Concentrates, and Isolates of Brachytrupes membranaceus (Orthoptera: Gryllidae) (Drury: 1773) and Macrotermes subhyalinus (Isoptera: Blattodea) (Rambur: 1842) from Burkina Faso

Brachytrupes membranaceus Bases and Macrotermes subhyalinus are edible insects in Burkina Faso.Our research aimed to evaluate the nutritional composition and functional properties of the defatted flours, protein concentrates, and isolates of Brachytrupes membranaceus and Macrotermes subhyalinus.Proximate and mineral composition were determined acco

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